The most popular GH optimization combination — GHRH and GHRP working synergistically for maximum physiological GH release.
The CJC-1295 No DAC / Ipamorelin combination is the most widely used GH optimization protocol. CJC-1295 No DAC provides the GHRH stimulus while Ipamorelin amplifies the GH pulse, producing synergistic GH release with physiological pulsatility.
Subcutaneous injection
0.5 mg to 1.5 mg
“The most popular GH optimization combination — GHRH and GHRP working synergistically for maximum physiological GH release.”
CJC-1295 No DAC activates GHRH receptors to stimulate GH synthesis. Ipamorelin activates GHS-R1a to amplify the GH pulse. The combination produces 3–5x greater GH release than either peptide alone while maintaining natural pulsatility.
0.5 mg to 1.5 mg
2–3x daily
8–16 weeks
Subcutaneous injection
Inject both peptides simultaneously or within minutes of each other. Administer on empty stomach. Bedtime dose is most important. Monitor IGF-1 every 3 months.
Per prescriber instructions or individual vial reconstitution.
Lyophilized: refrigerate. Reconstituted: refrigerate and use within 30 days.
When sourcing CJC-1295 No DAC / Ipamorelin for research purposes, the following quality benchmarks should be verified before use.
>98% (verified by HPLC)
Must be provided by supplier
<0.1 EU/mg (prevents bacterial contamination)
Manufactured in cGMP-certified facility
Independent lab verification preferred
Lyophilized: refrigerate. Reconstituted: refrigerate and use within 30 days.
The statements made within this website have not been evaluated by the US Food and Drug Administration. The products and information provided are not intended to diagnose, treat, cure, or prevent any disease. This website is intended for educational and research purposes only. Many peptides described on this site are not approved by the FDA for human therapeutic use and are classified as research chemicals. Nothing on this site constitutes medical advice.
Multiple animal studies and/or early human trials. Reasonable confidence in mechanism, but human data is limited.
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Category
Status
Dose
0.5 mg to 1.5 mg
Frequency
2–3x daily
Cycle
8–16 weeks
Peptides
Protocols
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FDA Disclaimer: The statements made within this website have not been evaluated by the US Food and Drug Administration. The products and information provided are not intended to diagnose, treat, cure, or prevent any disease. This website is intended for educational and research purposes only. Many compounds described on this site are not approved by the FDA for human therapeutic use. Some are available only as compounded preparations or as materials sold for laboratory use, and several are on FDA's Category 2 list for significant safety risks. Nothing on this site constitutes medical advice or a recommendation to use any compound described.